临床神经外科杂志2013，Vol.10Issue(4)：239-241,3.DOI:10.3969/j.issn.1672-7770.2013.04.018
生物蛋白海绵在额叶癫痫手术中的应用
Application of biologic protein sponge in surgery for patients with frontal lobe epilepsy
张绍辉 1梁树立 1侯月华 2张志文1
作者信息
- 1. 100048北京,解放军总医院第一附属医院神经外科
- 2. 河北省香河县人民医院神经外科
- 折叠
摘要
Abstract
Objective To compare the efficiency and safety of biologic protein sponge with collagen sponge in surgery for patients with frontal lobe epilepsy,and explore the value of biologic protein sponge in epileptic surgery.Methods This cohort included 28 patients with frontal lobe epilepsy in biologic sponge group,who underwent anterior frontal lobectomy and used biologic protein sponge as hemostasis material in operation in our epileptic center.And control group,collagen sponge group,included another 28 cases,which underwent anterior frontal lobectomy and used collagen protein sponge as hemostasis material.The volumes of incision draining in 24 hours after operation,body temperature at morning,and numbers of red blood cells and white blood cells in cerebral spine fluid in third day after surgery were analyzed after 15 months treatment.Results Volumes of incision draining in 24 hours after operation in biologic sponge group was significantly lower than that in collagen sponge group.Number of red blood cells in cerebral spine fluid in the third day after surgery in biologic sponge group was also significantly lower than that in collagen sponge group; significant difference was found in percentage of porencephaly in patients with opening the lateral ventricle between two groups.Significant difference was not found in body temperature and number of white blood cells in cerebral spine fluid in 3 days after operation.Conclusion Biologic sponge can reduce bleeding of brain incision,and promote healing of dura,and decline the possibility of porencephaly after opening of lateral ventricle during anterior frontal lobectomy.关键词
癫痫外科/额叶癫痫/止血材料/生物蛋白海绵Key words
epileptic surgery /frontal lobe epilepsy/hemostasis material /biologic protein sponge分类
医药卫生引用本文复制引用
张绍辉,梁树立,侯月华,张志文..生物蛋白海绵在额叶癫痫手术中的应用[J].临床神经外科杂志,2013,10(4):239-241,3.
