临床输血与检验2013，Vol.15Issue(3)：224-227,4.DOI:10.3969/j.issn.1671-2587.2013.03.010
微柱凝胶技术在新生儿ABO溶血病检测中的应用
Application of Microcolumn Gel Technique in Detection of Neonatal Hemolytic Disease
朱梅 1陶存武 1张循善 2许伟2
作者信息
- 1. 230001 安徽省合肥市第一人民医院核医学科
- 2. 安徽医科大学第一附属医院输血科
- 折叠
摘要
Abstract
Objective To investigate and analyze the application of microcolumn gel technique in screening ABO hemolytic disease of the newborn(ABO-HDN).Methods Direct antiglobulin test,antibody release test and free antibody test were performed in 580 cases suspected of ABO-NHD by using microcolumn gel assay.Results The total positive rate for ABO-HDN was 17.6％(102/580).In 102 ABO-NHD cases,56 cases(18.0％)was A blood type and 46 cases was B blood type.There was no significant difference in the distribution rates of A blood type and B blood type(17.1％)in ABO-NHD cases(P＞0.05).Moreover,the sensitivity of direct antiglobulin test was the lowest,while the sensitivity of the elution test was the highest.The detection rate of ABO-HDN in newborns aged less than or equal to 3 days was higher than that in those aged greater than 3 days and less than/equal to 7 days(22.9％ vs 10.5％)and those aged greater than 7 days(22.9％ vs 3.9％).Conclusions With the advantages of simple to handle,easy to use,less specimen usage,high sensitivity and specificity,obvious results of negative and positive and easy to preserve the results,MGT can provide reliable basis for HDN diagnosis,it is worth popularizing.关键词
微柱凝胶技术/新生儿溶血病Key words
Micro-column gel technology/Hemolytic disease of newborn分类
医药卫生引用本文复制引用
朱梅,陶存武,张循善,许伟..微柱凝胶技术在新生儿ABO溶血病检测中的应用[J].临床输血与检验,2013,15(3):224-227,4.
