天然产物研究与开发2013，Vol.25Issue(6)：841-845,5.
响应面法优化细果角茴香中总黄酮的超声提取条件
Optimization of Ultrasonic-assisted Extraction of Total Flavonoids from Hypecoum leptocarpum Hook.f.et Thoms by Response Surface Analysis
摘要
Abstract
Response surface methodology(RSM) is applied to optimize ultrasonic-assisted extraction process of total flavonoids from Hypecoum leptocarpum Hook.f.et Thoms.Based on single experiments,the concentration of ethanol,ratio of liquid to solid,and extraction time are selected for Box-Behnken central composite designing.RSM is employed to study the effect of these factors on the yield of total flavonoids.The results indicates that the optimal extraction conditions are 33∶1 mL/g as the ratio of liquid to solid,58％ of aqueous ethanol,with 34.5 min extraction.Under the optimized conditions,the extraction yield of total flavonoids is up to 1.525％.关键词
细果角茴香/总黄酮/超声提取/响应面Key words
Hypecoum leptocarpum Hook.f.et Thoms /total flavonoids/ ultrasonic extraction/ response surface methodology分类
医药卫生引用本文复制引用
张秋龙,梁永欣,李文聪,索有瑞,丁晨旭,王洪论..响应面法优化细果角茴香中总黄酮的超声提取条件[J].天然产物研究与开发,2013,25(6):841-845,5.基金项目
青海省科技厅项目(2010-J-111 2010-Z-719) （2010-J-111 2010-Z-719）
