湖北医药学院学报2013,Vol.32Issue(3):245-247,3.DOI:10.7543/j.issn.1006-9674.2013.03.015
乙肝肝硬化患者FIB-4指数与Child-Pugh分级相关性研究
The Correlation of FIB-4 Index with Child-Pugh Classification in Patients with HBV-related Cirrhosis
丁德平 1孟忠吉 1柯昌征 1李东 1陈悦1
作者信息
- 1. 湖北医药学院附属太和医院感染科,湖北十堰 442000
- 折叠
摘要
Abstract
Objective To investigate the correlation between FIB-4 index and Child-Pugh classification in patients with HBV-related cirrhosis.Methods The clinical data of 112 patients with HBV-related cirrhosis were restrospectively analyzed.The patients were divided into three groups(group A,B,C) according to Child-Pugh classification.FIB-4 index were calculated based on age,levels of ALT and AST,platelet counts.The Spearman's rank correlation was used to analyze the relationship between FIB-4 index and Child-Pugh classification.Results There was a significant difference in the FIB-4 index among group A,B and C(all P <0.01).The Spearman's rank correlation analysis demonstrated that the coefficient correlation between FIB-4 index and Child-Pugh classification was 0.817(P <0.01).Conclusion The FIB-4 index is closely conelated to Child-Pugh classification in patients with HBV-related cirrhosis.The FIB-4 index is a simple,objective and effective method for assessing the severity and prognosis of patients with HBV-related cirrhosis.关键词
FIB-4指数/Chlid-Pugh分级/肝硬化Key words
FIB-4 index/ Child-Pugh classification/ Liver cirrhosis引用本文复制引用
丁德平,孟忠吉,柯昌征,李东,陈悦..乙肝肝硬化患者FIB-4指数与Child-Pugh分级相关性研究[J].湖北医药学院学报,2013,32(3):245-247,3.