中国实用内科杂志2013，Vol.33Issue(7)：552-555,4.
脂质蓄积指数对代谢综合征的评估价值研究
Lipid accumulation product as an effective marker for metabolic syndrome
段凤仪 1李蓉 1张素华 1任伟 1汪志红 1龚莉琳 1李启富1
作者信息
- 1. 重庆医科大学附属第一医院内分泌科,重庆400016
- 折叠
摘要
Abstract
Objective To explore the efficacy of lipid accumulation product (LAP) in identifying metabolic syndrome (MS),compared with such traditional markers as body mass index (BMI),waist circurmference (WC) or waist hip ratio (WHR).Methods This research was a cross-sectional study,including 3467 subjects aged 25 to 85 years from an urban community of Chongqing city.Metabolic syndrome was diagnosed according to international diagnostic criteria 2009.Body fat indexes,including WC,TG,BMI,WHR,TG/HDL-C,HOMA-IR and LAP were compared between the MS group and non-MS group.Receiver operating characteristic curve analysis was conducted to detect the best predictive variable to identify MS.Results (1) LAP was significantly elevated (P ＜ 0.O1) among all sub-groups of MS patients.(2) LAP showed the largest area under the curve to identify MS (0.91 ± 0.01 [95 ％ C I 0.89-0.92] in males,0.93 ± 0.01 [95 ％ C I 0.91-0.94] in females).For both males and females,the cut-off values of LAP exhibited high sensitivity and specificity for MS identification.(3) The subjects stratified according to fifteen years of life,LAP also showed the largest area under the curve in each age group in males,and showed the largest in the 25-40 and 56-70 years of age in females.Conclusion LAP is closely related with HOMA-IR and MS.LAP is proved to be the best body fat marker to identify MS,compared with other body fat indexes.关键词
脂质蓄积指数/代谢综合征/体重指数/胰岛素抵抗Key words
lipid accumulation product/metabolic syndrome/body mass index/insulin resistance分类
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段凤仪,李蓉,张素华,任伟,汪志红,龚莉琳,李启富..脂质蓄积指数对代谢综合征的评估价值研究[J].中国实用内科杂志,2013,33(7):552-555,4.
