中国实用内科杂志2013，Vol.33Issue(8)：644-647,4.
阻塞性睡眠呼吸暂停低通气综合征内分泌代谢昼夜变化研究
Diurnal metabolic changes in patients with obstructive sleep apnea hypoventilation syndrome
摘要
Abstract
Objective To explore the endocrine metabolic features of patients with obstructive sleep apnea hypoventilation syndrome.Methods The circadian metabolic data of endocrine factors including 27 cases of OSAHS patients and 10 healthy controls diagnosed by respiratory monitoring through polysomnography in respiratory department of the 1st affiliated hospital of China Medical University from January to October in 2012 were summarized.Results (1) The HLD-C levels of severe OSAHS patients were significantly different from those of the controls,and CHO levels were higher in severe OSAHS patients than in the mild to moderate ones; (2) Significant differences in GLU and UA measured before bed and after waking up were observed respectively between severe OSAHS and controls ; (3) The awake OX-LDL was higher than that measured before sleep in severe OSAHS patients; (4) The awake OX-LDL level in OSAHS patients was higher than that in healthy controls.Conclusion The patients of obstructive sleep apnea hypopnea syndrome with changes of endocrine factor is more prone to developing AS.关键词
阻塞性睡眠呼吸暂停低通气综合征/内分泌代谢/昼夜变化Key words
obstructive sleep apnea hypoventilation syndrome/endocrine metabolism/diurnal changes分类
医药卫生引用本文复制引用
秦铮,孔德磊,王玮..阻塞性睡眠呼吸暂停低通气综合征内分泌代谢昼夜变化研究[J].中国实用内科杂志,2013,33(8):644-647,4.基金项目
辽宁省教育厅科学研究一般项目(L2012274) （L2012274）
