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结直肠癌肝转移化疗和靶向治疗进展

沈琳

中国实用外科杂志2013,Vol.33Issue(8):674-675,2.
中国实用外科杂志2013,Vol.33Issue(8):674-675,2.

结直肠癌肝转移化疗和靶向治疗进展

Advance of chemotherapy and targeted therapy in colorectal liver metastases

沈琳1

作者信息

  • 1. 北京大学肿瘤医院消化内科,北京100142
  • 折叠

摘要

Abstract

Advances in the treatment of colorectal liver metastases (CRLM) have benefited from the development of multidisciplinary treatment.But many problems are still unresolved in clinical practice including optimization of chemotherapy,advantages and disadvantages of combination of targeted therapy with chemotherapy,safety and chemotherapy timing,etc.Especially after the failure of CRLM adjuvant chemotherapy or targeted therapy,there is a growing concern about preoperative treatment and conversion therapy.Effective chemotherapy can provide more opportunities of radical resection and prolonged survival.Rational option of combination of targeted therapy with chemotherapy,correct chemotherapy duration and withdrawal time are the keys to improve management level of CRLM.

关键词

结直肠癌/肝转移/化疗/靶向治疗

Key words

colorectal cancer/ liver metastases / chemotherapy / targeted therapy

分类

医药卫生

引用本文复制引用

沈琳..结直肠癌肝转移化疗和靶向治疗进展[J].中国实用外科杂志,2013,33(8):674-675,2.

中国实用外科杂志

OA北大核心CSCDCSTPCD

1005-2208

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