中药材2013，Vol.36Issue(6)：924-929,6.
基于UPLC-TOF/MS的苍耳子不同部位化学成分研究
Study on the Chemical Composition in Different Parts of Xanthii Fructus Based on UPLC-TOF/MS
摘要
Abstract
Objective:To analyze the chemical composition in Xanthii Fructus by UPLC-ESI-TOF/MS.Methods:UPLC-ESI-TOF/MS was used to analyze the samples in positive and negative mode,Masslynx V4.1 workstation was used to analyze data.Through calculating accuracy mass and isotopic fit value of the molecular ion cluster,molecular formula was confirmed.Results:33 peaks were detected from the water extract of Xanthii Fructus,11 peaks were identified by reference substance and elemental composition analysis.22 peaks were from Xanthim thorn,31 peaks were from the fruit without stab,20 of them were identical.Conclusion:This method is convenient,accurate and specific,and can be used to find out which parts the component belong to in Xanthium.This study can provide scientific evidence to distinguish the toxic component of Xanthii Fructus and guide clinical medication safety.关键词
苍耳子/UPLC-TOF/MS/化学成分Key words
Xanthii Fructus / UPLC-TOF/MS / Chemical composition分类
医药卫生引用本文复制引用
刘树民,曹敏,武斌,卢芳..基于UPLC-TOF/MS的苍耳子不同部位化学成分研究[J].中药材,2013,36(6):924-929,6.基金项目
国家自然科学基金(30873435) （30873435）
黑龙江中医药大学优秀创新人才支持计划资助 （）
