国际医药卫生导报2013，Vol.19Issue(17)：2714-2717,4.DOI:10.3760/cma.j.issn.1007-1245.2013.17.023
儿童传染性单核细胞增多综合征的病因分析和临床特征研究
The analysis of etiology and clinical features of children infectious mononucleosis syndrome
摘要
Abstract
Objective To explore etiology and clinical features of children infectious mononucleosis syndrome(IMS)and improve curative effect and shorten course of treatment by corresponding treatment according to different pathogens.Methods 35 cases of EB virus(EBV)-VCA-IgM,EBV-VCA-IgA negative were diagnosed with children infectious mononucleosis syndrome,and used ELISA method to detect their serum antibodies with mycoplasma pneumonia(MP-IgM),cytomegalovirus(CMV-IgM),adenovirus antibody (ADV-IgM),Coxsackie virus antibody(CBV-IgM),Toxoplasma antibody(Tox-IgM),parvovirus antibody (B19-IgM)and hepatitis B virus(HBsAg).Selected 25 cases of children infectious mononucleosis(IM)with EBV infection as control group.Results There were 12 cases of MP-IgM positive(more than 1:80)(34.3％),5cases of CMV-IgM positive(14.3％),2 cases of ADV-IgM positive(5.7％),1 case of CBV-IgM positive(5.7％),1 case of parvovirus antibody(B19-IgM)positive(5.7％),3 cases of hepatitis B virus(HBsAg)positive(7.9％)respectively in IMS group.There were significant differences in lymphadenectasis,myocardial enzymes,white blood cell count and atypical lymph cell count between IMS group and IM group(P ＜ 0.05).Conclusion MP and CMV are the most common etiology of IMS.It is important to diagnose and use azithromycin,erythromycin and other macrolides against mycoplasma and ganciclovir anti-virus as early as possible.关键词
传染性单核细胞增多综合征/病原学/临床特征/儿童Key words
Infectious mononucleosis syndrome/Etiology/Clinical features/Children引用本文复制引用
刘玲,黄斌明,夏曦,江志贵..儿童传染性单核细胞增多综合征的病因分析和临床特征研究[J].国际医药卫生导报,2013,19(17):2714-2717,4.
