国际医药卫生导报2013，Vol.19Issue(23)：3616-3619,4.DOI:10.3760/cma.j.issn.1007-1245.2013.23.030
吉西也滨联合长瑞滨、地塞米松在复发性非霍奇金淋巴瘤治疗中的作用
Gemcitabine in combination with vinorelbine and dexamethasone for relapsed non-Hodgkin's lymphoma
吴非常 1吴祥成 1李涛 1莫奉山 1李宗泰1
作者信息
摘要
Abstract
Objective To explore the clinical value of Gemcitabine in combination with vinorelbine and dexamethasone in the treatment of relapsed non-Hodgkin's lymphoma.Methods 18 patients with nonHodgkin's lymphoma were treated with gemcitabine hydrochloride,Vinorelbine,and dexamethasone.The efficacy,adverse reactions,and tumor progression were observed.Results The overall effective rate was 55.56％.The complete remission rate was 22.22％.There was no statistical difference(x2 =0.969,P =0.809)in classification between B and T cells.Bone marrow suppression was the common toxicity.5 patients had gastrointestinal reactions.1 patient occurred mild liver dysfunction.After two years follow-up,it showed that 10 patients had no tumor progression,the other 8 patients (44.4％) progressed in tumor in average 4.9 months.Conclusions Gemcitabine in combination with vinorelbine and dexamethasone for non-Hodgkin's lymphoma has a good recent efficacy,few adverse reactions,and a low recurrence rate.关键词
吉西他滨/长春瑞滨/地塞米松/复发性非霍奇金淋巴瘤/疗效/肿瘤进展时间Key words
Gemcitabine/ Vinorelbine/ Dexamethasone/ Relapsed non-Hodgkin's lymphoma/Efficacy/ Tumor progression time引用本文复制引用
吴非常,吴祥成,李涛,莫奉山,李宗泰..吉西也滨联合长瑞滨、地塞米松在复发性非霍奇金淋巴瘤治疗中的作用[J].国际医药卫生导报,2013,19(23):3616-3619,4.
