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胃癌合并肿瘤相关性微血管病性溶血性贫血一例报道并文献复习

孙明东 郑永青 李尊昌 王强

国际医药卫生导报2014,Vol.20Issue(5):664-668,5.
国际医药卫生导报2014,Vol.20Issue(5):664-668,5.DOI:10.3760/cma.j.issn.1007-1245.2014.05.026

胃癌合并肿瘤相关性微血管病性溶血性贫血一例报道并文献复习

Gastric cancer-related microangiopathic hemolytic anemia: a case report and literature review

孙明东 1郑永青 1李尊昌 1王强2

作者信息

  • 1. 256610 滨州医学院附属滨州市人民医院血液科
  • 2. 256610 滨州医学院附属滨州市人民医院普外科
  • 折叠

摘要

Abstract

Objective To investigate the clinical features and prognosis of gastric cancer-related microangiopathic hemolytic anemia in order to improve the recognition of the disease.Methods A case ofgastric cancer-related microangiopathic hemolytic anemia was reported and the related domestic literatures were reviewed.Results We reviewed and analyzed 18 cases of gastric cancer-related microangiopathic hemolytic anemia,we reported 1 case and reviewed the other 17 cases.10 male(55.56%),8 female(44.44%),the ratio was 1.13:1,the median patient age was 41 years (23-68),all were diagnosed as glandular cancer by gastroscopic biopsies,and 8 cases were metastatic carcinoma of bone marrow.The clinical features were progressive anemia and soy urine,mostly with lymph node and other distant metastasis.The several anemia and schistocytes were described in all cases.These patients had short survival,the median survival time was 23 days.Conclusion Gastric cancer-related microangiopathic hemolvtic anemia was uncommon,with the following characteristics:the intravascular hemolytic anemia is not consistent with primary disease; metastasized widely; glandular cancer; several anemia.The prognosis is poor,the survival time is shorter; chemotherapy can improve the prognosis.

关键词

胃癌/微血管病性溶血性贫血/转移

Key words

Gastric cancer/ Microangiopathic hemolytic anemia/ Metastasis

引用本文复制引用

孙明东,郑永青,李尊昌,王强..胃癌合并肿瘤相关性微血管病性溶血性贫血一例报道并文献复习[J].国际医药卫生导报,2014,20(5):664-668,5.

国际医药卫生导报

1007-1245

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