中国病理生理杂志2014，Vol.30Issue(3)：551-557,7.DOI:10.3969/j.issn.1000-4718.2014.03.030
运动性心脏肥大：AT1受体、细胞自噬和 miRNAs 的调节
Cardiac hypertrophy induced by exercise training:the function of AT1 receptor, autophagy and miRNAs
摘要
Abstract
As a mechanical and exogenous stimulus , exercise training induces cardiac physiological hypertro-phy, and the cardiac structure is changed slowly , steadily and coordinately.Simultaneously, energy metabolism and func-tion of the cardiac muscle are also improved .These are positive adaptations in the heart when experiencing endurance exer -cise training.Recently, angiotensinⅡtype 1 (AT1) receptor, autophagy and miRNAs are all considered as important reg-ulators to cardiac hypertrophy induced by exercise training at different molecular levels .Fully understanding the relations and the important role of AT1 receptor, autophagy and miRNAs in cardiac physiological hypertrophy will further enrich the signaling pathway of cardiac hypertrophy induced by exercise training .关键词
运动训练/心脏肥大/血管紧张素II1型受体/自噬/微小RNAKey words
Exercise training/Cardiac hypertrophy/Angiotensin II type 1 receptor/Autophagy/MicroRNAs分类
医药卫生引用本文复制引用
钱帅伟,张瑞萍,张安民..运动性心脏肥大：AT1受体、细胞自噬和 miRNAs 的调节[J].中国病理生理杂志,2014,30(3):551-557,7.基金项目
广东省科技计划(No.2012B031800076) （No.2012B031800076）
