分析化学2014，Vol.42Issue(3)：403-408,6.DOI:10.3724/SP.J.1096.2014.30796
食品罐内壁涂料中双酚-二缩水甘油醚的快速检测和迁移规律
Rapid Determination of Bisphenol Diglycidyl Ethers and Its Migration Regulations in Interior Coating of Food Cans
摘要
Abstract
A rapid and simple ultra performance liquid chromatographic method for determination the specific migration of bisphenol A diglycidyl ether ( BADGE ) , bisphenol F diglycidyl ether ( BFDGE ) and their derivatives in food simulants was developed. Water, 3% acetic acid, 10% ethanol and sunflower oil were used as food simulants to simulate the specific migration of bisphenol diglycidyl ethers from interior coating of food cans after 10 days storage at 60℃. After the migration period, the aqueous food simulants were directly measured without any further purification, while the sunflower oil simulant was extracted by acetonitrile followed by cleaning up using solid phase extraction. Among the migration process, BADGE and bisphenol A (3-chloro-2-hydroxypropyl)glycidyl ether (BADGE·HCl) migrated into aqueous simulants were hydrolysed into bisphenol A bis ( 2, 3-dihydroxypropyl ) ether ( BADGE · 2H2 O ) and bisphenol A ( 3-chloro-2-hydroxypropyl) (2,3-dihydroxypropyl) ether (BADGE·H2O·HCl), respectively. However, BADGE and BADGE·HCl migrated into sunflower oil were not hydrolysed. The calibrating curves showed a good linearity from 0. 05 to 10 mg/L for all the 9 target compounds. The detection limits of the method for aqueous food simulants and sunflower oil stimulant were 5μg/L and 20μg/kg, respectively. The method was applied to the determination of bisphenol diglycidyl ethers migrated from 10 kinds of food cans which were intended to contact with food. The results indicate that BADGE and its derivatives were detected at 5 of the cans, and the specific migration of BADGE(or BADGE·2H2O)and BADGE·HCl(or BADGE·H2O·HCl)in 1 cans even exceed the responding limitation regulated in EC/1895/2005 .关键词
食品罐/双酚-二缩水甘油醚/特定迁移量/超高效液相色谱Key words
Food cans/Bisphenol diglycidyl ether/Specific migration/Ultra performance liquid chromatography引用本文复制引用
曹国洲,陈少鸿,肖道清,朱晓艳,马明,刘在美..食品罐内壁涂料中双酚-二缩水甘油醚的快速检测和迁移规律[J].分析化学,2014,42(3):403-408,6.基金项目
本文系宁波市自然科学基金(No.2010A610011)和质检总局科技计划(Nos.2011IK036,2012IK208)资助项目 （No.2010A610011）
This work was supported by the Natural Science Foundation of Ningbo,China (No.2010A610011) （No.2010A610011）
