癌变·畸变·突变Issue(6)：430-434,5.DOI:10.3969/j.issn.1004-616x.2013.06.006
韭籽多糖对食管癌EC9706细胞增殖和凋亡的影响
The effects of Leek seed polysaccharide on the proliferation and apoptosis of human esophagus cancer cell EC9706
摘要
Abstract
OBJECTIVE: To investigate the effects of Leek seed polysaccharide on the proliferation and apoptosis of human esophagus cancer cell EC9706. METHODS:Flow cytometry,Hoechst33258 staining,transmission electron microscope and DNA gel electrophoresis were used. RESULTS:Proliferation of EC9706 cells was significantly inhibited by Leek seed polysaccharide at the dose of 40μg/mL(P<0.05). Moreover,after 48 hour of treatment by Leek seed polysaccharide,obvious characteristic features of apoptosis and DNA ladder were also induced. CONCLUSION:Leek seed polysaccharide could inhibit EC9706 cell proliferation and induce its apoptosis.关键词
韭籽多糖/人食管癌EC9706细胞/增殖/凋亡Key words
Leek seed polysaccharide/human esophagus cancer cell EC9706/proliferation/apoptosis分类
医药卫生引用本文复制引用
张红波,屈二军,杨海波,宋巍,陈兰英..韭籽多糖对食管癌EC9706细胞增殖和凋亡的影响[J].癌变·畸变·突变,2013,(6):430-434,5.基金项目
河南省基础与前沿项目(132300410306) （132300410306）
