滨州医学院学报Issue(6)：424-425,428,3.
左西孟旦在缺血性心肌病顽固性心力衰竭患者经皮冠状动脉介入治疗中的应用研究
Percutaneous coronary intervention of Levosimendan in ischemic cardiomyopathy patients with refractory heart failure
郭明 1杨大成 1张建伟1
作者信息
- 1. 滕州市中心人民医院心血管内科 滕州 277500
- 折叠
摘要
Abstract
Objective To study the effects of levosimendan in ischemic cardiomyopathy patients with refractory heart failure of per -cutaneous coronary intervention .Methods Eighty cases of coronary intervention in patients with chronic heart failure were randomly divided into treatment group (40 cases) and control group (40 cases).The control group received conventional therapy while treatment group patients were given levosimendan injection two days before surgery .All patients underwent coronary angiography to determine the extent of coronary artery disease and the degree of stenosis ,and received intervention .Postoperative creatinine levels were observed , and heart function situation was followed up,including the 6-minute walk test,left ventricular end-diastolic diameter (LVEDD),left ventric-ular ejection fraction (LVEF), etc.Results Treatment group completed a total of 38 cases of complete revascularization,while the control group completed a total of 25cases of complete revascularization with the difference statistically significant (P<0.05).Clinical symptoms significantly reduced in the control and treatment group .Treatment group improved heart function more obviously than that before the operation ( P<0.05 ) .Creatinine level after the operation in treatment group was lower than that in control group ( P<0.05).Conclusion Ischemic cardiomyopathy refractory heart failure patients injected levosimendan before the intervention increased their tolerance ,increased the success rate of complete blood flow ,reduced the risk of postoperative complications ,improved significantly postoperative cardiac function and renal function levels to save ischemic myocardium to an extreme degree .关键词
左西孟旦/缺血性心肌病/顽固性心力衰竭/介入治疗Key words
levosimendan/Ischemic cardiomyopathy/Refractory heart failure/Intervention分类
医药卫生引用本文复制引用
郭明,杨大成,张建伟..左西孟旦在缺血性心肌病顽固性心力衰竭患者经皮冠状动脉介入治疗中的应用研究[J].滨州医学院学报,2013,(6):424-425,428,3.
