重庆医学Issue(26)：3112-3114,3.DOI:10.3969/j.issn.1671-8348.2013.26.013
早产儿体液免疫变化及影响因素研究
Study on changes and influence of humoral immunity in premature infants
摘要
Abstract
Objective To study changes of humoral immunity of the premature infants in different pathological conditions and detect the reason of the deficiency of humoral immunity in premature infants .Methods Two hundred and forty-six prematur were enrolled and 30 healthy neonates were selected as control group .The percentages of IgG ,IgA ,IgM and comp lement C3 ,C4 were detected by full automatic biochemical analyzer .Results The results showed that IgG ,IgM ,IgA ,C3 and C4 in the premature in-fants were lower than those in the normal term infants and there was a highly significant difference with the decrease of fetal age . IgG ,IgM ,IgA ,C3 and C4 of the group of the premature infants ranging from 32 to 36 weeks had reduced in different degree ,rela-tive to the groups of BW <2 000 g ,hypertension during pregnancy ,cesarean section(P<0 .05) .Conclusion The results showed that function of humoral immunity in the premature infants was depressed and low gestational age ,low birth weight ,cesarean sec-tion and hypertension during pregnancy may be the leading cause of the deficiency of humoral immunity .关键词
婴儿 ,早产/免疫/补体C3/补体C4Key words
infant ,premature/immunity/complement C3/complement C4引用本文复制引用
王春红,魏建和,刘振奎,肖佩霞,张雅静,袁二伟..早产儿体液免疫变化及影响因素研究[J].重庆医学,2013,(26):3112-3114,3.基金项目
张家口市科技局课题资助项目（12110045D-2）。 （）
