重庆医学Issue(36)：4397-4399,3.DOI:10.3969/j.issn.1671-8348.2013.36.014
缺血修饰清蛋白与冠心病相关性研究
The study on the relatioship between on ischemia modified albumin and coronary heart disease
摘要
Abstract
Objective To evaluate the value of ischemia modified albumin (IMA) in the diagnosis of coronary heart disease (CHD) and the correlation between IMA levels and the pathological scope of coronary atherosclerosis .Methods A total of 88 coro-nary heart disease(CHD) patients diagnosed by coronary arteriongraphy (CAG) were selected ,including stable angina pectoris (16 cases)(SA group) and acute coronary syndrome (72 cases)(ACS group) .ACS group was further divided into 3 groups :unstable an-gina pectoris(30 cases)(UA group) ,non-ST-elevation myocardial infarction (19 cases) (NSTEMI group) ,ST-elevation myocardial infarction(23 cases) (STEMI group) .According to the results of CAG ,CHD patients were divided into 3 groups:1 vessel lesion group ,2 vessels lesion group and 3 vessels lesion group ,and 60 healthy physical cases were selected as control group .Results IMA in the CHD group was significantly higher than in control group (P<0 .05) .IMA in the ACS group was higher than SA group (P<0 .05) .IMA in the NSTEMI group and STEMI group were significantly higher than UA group (P<0 .05) .IMA levels and the degree of coronary atherosclerosis were significantly positively correlated (P<0 .05 ,r=0 .570) .When the cut-off value of IMA was 80 .10 U/mL ,the area under the curve was 0 .869 ,the specificity was 98 .4% and the sensitivity was 65 .9% .Logistic regression a-nalysis showed that IMA was an independent predictor of CHD .Conclusion IMA has a high negative predictive value in the diag-nosis of CHD ,there was a significantly positive correlation between IMA level and the pathological scope of coronary atherosclero-sis .关键词
缺血修饰清蛋白/冠心病/冠状动脉疾病/急性冠状动脉综合征Key words
ischemia modified albumin/coronary heart disease/coronary artery disease/acute coronary syndrome引用本文复制引用
邵江,牟华明,庞小华,李俊..缺血修饰清蛋白与冠心病相关性研究[J].重庆医学,2013,(36):4397-4399,3.基金项目
重庆市卫生局医学科研计划项目(2011-2-596) （2011-2-596）
