重庆医学Issue(1)：33-34,38,3.DOI:10.3969/j.issn.1671-8348.2014.01.011
中青年颈动脉粥样硬化斑块形成患者中医证型与血浆髓过氧化物酶、颈动脉斑块类型的关系
The relationship among TCM syndrome classification,MPO and the type of carotid plaque in young and middle-aged patients with CAS plaque
摘要
Abstract
Objective To investigate the relationship among TCM syndrome classification ,M PO and the type of carotid plaque in young and middle-aged patients with CAS plaque .Methods To diagnose syndrome differentiation of TCM of 120 cases of young and middle-aged patients with CAS plaque and determine the level of plasma MPO with ELISA ;use Carotid Artery Doppler ultra-sound to detect the patterns of Carotid Artery plaque .Then compare the plasma MPO level in different patients with different syn-dromes of phlegm turbid retention syndrome ,blood stasis ,energy deficiency syndrome ,and deficiency of Qi ,and the changes in vari-ous types of plaque of flat plaque ,soft plaque ,hard plaque and mixed plaque .Results The MPO level of young and middle-aged pa-tients with CAS plaque increased significantly as compared with health controls (P<0 .05) .Both the numbers and the ratio of the plasma MPO level ,cases of cervical artery soft plaque and mixed plaque detected in patients with phlegm turbid retention syndrome and blood stasis syndrome increased significantly compared to the patients with energy deficiency syndrome and deficiency of Qi syndrome (P<0 .01) .Conclusion Plasma MPO level of young and middle-aged patients with CAS may reflect the degree of CAS and the stability of plaque to a certian extent .There are some specific effect about plasma MPO level and the changes of carotid soft plaque and mixed plaque in patients with phlegm turbid retention syndrome and blood stasis .It provides objective basis for syn-drome differentiation of TCM and provides the theoretic and experimental basis for early diagnose and treatment of CAS .关键词
颈动脉粥样硬化/髓过氧化物酶/中青年/中医证型Key words
carotid atherosclerosis/myeloperoxidase/young and middle-aged/TCM syndrome classification引用本文复制引用
胡玉英,刘泰,胡跃强,张青萍,刘雪玲,陈薇,陈兴华..中青年颈动脉粥样硬化斑块形成患者中医证型与血浆髓过氧化物酶、颈动脉斑块类型的关系[J].重庆医学,2014,(1):33-34,38,3.基金项目
广西壮族自治区卫生厅重点科研课题（2010091）。 （）
