重庆医学Issue(3)：290-292,3.DOI:10.3969/j.issn.1671-8348.2014.03.013
儿童后部可逆性脑病综合征的MRI表现及发病机制探讨
MRI findings and pathogenesis exploration of posterior reversible encephalopathy syndrome in children
郑鹤琳 1蔡金华 1杜长国2
作者信息
- 1. 重庆医科大学附属儿童医院放射科 400014
- 2. 中国人民解放军77100部队后勤部门诊部，重庆400014
- 折叠
摘要
Abstract
Objective To analyze the MRI features of posterior reversible encephalopathy syndromes (PRES) in children and to explore its possible pathologic mechanism .Methods The clinical and imaging data of 10 patients with PRES were analyzed retro-spectively .All cases had underlying diseases including 5 cases of nephrotic syndrome ,2 cases of acute nephritis ,1 case of severe pneumonia complicated with high renin hypertension ,1 case of lymphoma chemotherapy and 1 case of hemophagocytic lymphohisti-ocytosis .Of 10 cases ,7 cases had hypertension .MR scanning was performed in all cases ,in which 2 cases underwent enhanced MR imaging and 2 cases underwent MR angiography(MRA) .Results MRI showed the lower signals on multiple T1W1 and the high signals on T2W1 in the cortical and subcortical regions of the bilateral occipital and parietal lobe (10 cases) ,bilateral frontal lobe(2 cases) ,temporal lobe(2 cases) ,basal ganglial area(1 case) and bilateral cerebellar hemispheres(1 case) .The lesions presented as low signal on T1WI and high signal on T2WI and T2 FLAIR images .4 cases showed the high signal on DWI and 2 cases showed mild enhancement after administration of gadalinium .MRA in 1 case was manifested as stenosis of the distal end of the basilar ar-tery and the left vertebral artery .The follow-up MRI demonstrated that the lesions were significantly diminished or disappeared . Conclusion The MRI image features of PRES are manifested by the white matter edema in the occipital lobe and patietal cortex and subcortex .Its pathogenesis is complex .The present theories can not entirely explain all the MRI findings .Children with serious un-derlying disease should be vigilant in PRES and the M RI examination should be early conducted .关键词
磁共振成像/后部可逆性脑病/儿童Key words
magnetic resonance imaging/posterior reversible encephalopathy syndrome/children引用本文复制引用
郑鹤琳,蔡金华,杜长国..儿童后部可逆性脑病综合征的MRI表现及发病机制探讨[J].重庆医学,2014,(3):290-292,3.
