重庆医学Issue(5):516-517,520,3.DOI:10.3969/j.issn.1671-8348.2014.05.002
不同负荷剂量右美托咪定对SICU患者镇静诱导期血流动力学的影响
The effects of dexmedetomidine for different loading dose on blood pressure of SICU patients conscious-sedation derivative phase
蒋正英 1吴桂新 1张宁 1袁建国1
作者信息
- 1. 重庆市肿瘤研究所重症医学科 400030
- 折叠
摘要
Abstract
Objective To observe the effects of dexmedetomidine for different loading dose on blood pressure of surgery inten-sive care unit(SICU) patients conscious-sedation derivative phase .Methods 60 patients after general anaesthesia were divided into routine dose group(dexmedetomidine 1 .00 μg/kg ,group C) ,middle dose group(dexmedetomidine 0 .75 μg/kg ,group M ) and low dose group(dexmedetomidine 0 .50 μg/kg ,group L) ,and the loading time were reset 10 min .sedative effect was evaluated by Ram-say sedation score .Record the mean arterial blood pressure of everyone before administration ,5 min after ,15 min after ,30 min af-ter ,60 min after .Results All patients achieved good conscious-sedation .Compared with pro-administration ,the mean arterial blood pressure of group C descend significantly .The mean arterial blood pressure of group M and L descend significantly ,and then they were recover over time .60 min after the treatment ,the mean arterial blood pressure in group C was significantly lower than group L and goup M (P<0 .05) .Conclusion Small dose dexmedetomidine can achieved good conscious-sedation for SICU patients .It has less influence on hemodynamics .关键词
重症监护病房/血流动力学/血压/清醒镇静Key words
intensive care unit/hemodynamics/blood pressure/conscious sedation引用本文复制引用
蒋正英,吴桂新,张宁,袁建国..不同负荷剂量右美托咪定对SICU患者镇静诱导期血流动力学的影响[J].重庆医学,2014,(5):516-517,520,3.