重庆医学Issue(5)：529-531,3.DOI:10.3969/j.issn.1671-8348.2014.05.007
血清前清蛋白、C反应蛋白及载脂蛋白A1对重症肺炎患者预后评估的价值
Evaluation of the prognosis of the patients with severe pneumonia by observing prealbumin, C-reactive protein and apolipoprotein A 1
摘要
Abstract
Objective To study the value of prealbumin(PAB) ,C reactive protein(CRP) and apolipoprotein A1(Apo A1) in e-valuating the prognosis of patients with severe pneumonia .Methods 63 cases of patients with severe pneumonia were selected ,and the fasting serum level of prealbumin ,C-reactive protein and apolipoprotein A1 were detected in 24 hours at the admission day ,and APACHE Ⅱ score was calcumulated .The patients were divided into group A (APACHEⅡscore <20) and group B(APACHEⅡscore≥20) ,with the incidence of MODS and mortality rate compared .The patients were divided into non-MODS group and MODS group .In addition ,the patients were divided into survival group and death group according to the prognosis .PAB ,CRP and Apo A1 in each group were compared .Results The incidence of MODS and mortality rate in group B (57 .9% ,47 .4% ) were higher than that in group A(24 .0% ,16 .0% )(P<0 .01 ,P<0 .05) .PAB and Apo A1 of patients in MODS group[(134 .13 ± 36 .20)mg/L , (0 .62 ± 0 .21)g/L] and death group[(129 .05 ± 52 .24)mg/L ,(0 .76 ± 0 .29)g/L] were respectively lower than that in non-MODS group[(215 .03 ± 72 .08)mg/L ,(1 .06 ± 0 .39)g/L] and survival group[(185 .52 ± 57 .63)mg/L ,(1 .15 ± 0 .36)g/L](P<0 .05) , while the CRP in MODS group(102 .37 ± 35 .65)mg/L and death group(96 .37 ± 34 .72)mg/L were higher than that in non-MODS group(69 .68 ± 32 .92)mg/L and survival group(62 .94 ± 38 .36)mg/L (P<0 .05) .Conclusion The measurement of PAB ,CRP and Apo A1 are valuable to evaluate the prognosis of the patients with severe pneumonia .关键词
前白蛋白/C反应蛋白值/载脂蛋白A-Ⅰ/预后/重症肺炎Key words
prealbumin/C-reactive protein/apolipoprotein A-Ⅰ/prognosis/severe pneumonia引用本文复制引用
林化,马春林,王荣辉,梁道业..血清前清蛋白、C反应蛋白及载脂蛋白A1对重症肺炎患者预后评估的价值[J].重庆医学,2014,(5):529-531,3.基金项目
广西壮族自治区卫生厅计划课题（Z2013194）。 （）
