重庆医学Issue(5)：582-583,586,3.DOI:10.3969/j.issn.1671-8348.2014.05.026
α7尼古丁受体介导100Hz电针调节自然杀伤细胞活性的实验研究
New evidences of α7nAChR participating in 100 Hz EA regulating NK cells activity
摘要
Abstract
Objective On the basis of previous experiments ,we try further to seek the new evidences of α7nAChR participating in 100 Hz electroacupuncture (EA ) regulating natural killer (NK ) cells activity .Methods α7nAChR antibody and the specificα7nAChR antagonist α-bungarotoxin (α-Bgt) were used to study the effect of α7nAChR on NK cell activity in 100 Hz EA mice .Re-sults Compared with 100 Hz EA group ,100 Hz EA plus α7nAChR-Ab group showed a significant enhanced in NK cell activity (P<0 .05) .100 Hz EA treated with 1 .5 or 3 .0 μg α-Bgt groups had higher NK cell activity than 100 Hz EA group(P<0 .01) . Conclusion α7nAChR is involved in 100 Hz EA modulation for immune function ,which provide the theoretical and practical basis for further clarifying and expanding the clinical application of EA .关键词
电针/自然杀伤细胞活性/α7尼古丁受体Key words
electroacupuncture/natural killer cell activity/α7nAChR引用本文复制引用
胡志苹,黄志华,黄诚..α7尼古丁受体介导100Hz电针调节自然杀伤细胞活性的实验研究[J].重庆医学,2014,(5):582-583,586,3.基金项目
国家自然科学基金资助项目（31060144）；江西省自然科学基金资助项目（2008GZY0067）。 （）
