重庆医学Issue(6)：668-670,3.DOI:10.3969/j.issn.1671-8348.2014.06.011
不同血液净化方式对尿毒症性皮肤瘙痒患者疗效的观察
Clinical observation on the treatment effect for pruritus in uremic patients by different dialysis modalities
李瑜祯 1曹勇1
作者信息
- 1. 武警重庆市总队医院肾内科，重庆400061
- 折叠
摘要
Abstract
Objective To study the effect of different dialysis modalities on pruritus in uremic patients .Methods Patients with maintenance hemodialysis who were suffered with severe cutaneous pruritus were randomly divided into hemodialysis group (HD group) ,hemodialysis combined with hemodiafiltration group (HD+ HDF group) ,hemodialysis and hemodiafiltration combined with hemoperfusion group (HD+ HDF+ HP group) .Plasma P3+ ,parathyroid hormone (PTH) and β2-microglobulin (β2-MG) were measured at pre-dialysis ,1 weeks ,4 weeks and 12 weeks after dialysis ,cutaneous pruritus was scored too .Results Compared with pre-dialysis ,the level of plasma P3+ ,PTH ,β2-MG and the scores of cutaneous pruritus were significantly lower at 4 weeks and 12 weeks after dialysis in HD+ HDF+ HP group (P<0 .05) .The were statistically significant difference in P3+ ,PTH ,β2-MG and cu-taneous pruritus scores among 3 groups after 12 weeks (P<0 .05) .Conclusion HD+ HDF+ HP is superior to HD+ HDF in effi-ciently clear P3+ ,PT H andβ2-M G ,and relief cutaneous pruritus and itching .关键词
尿毒症/血液净化/皮肤瘙痒Key words
uremia/hemopurification/cutaneous pruritus引用本文复制引用
李瑜祯,曹勇..不同血液净化方式对尿毒症性皮肤瘙痒患者疗效的观察[J].重庆医学,2014,(6):668-670,3.
