重庆医学Issue(9)：1088-1089,1092,3.DOI:10.3969/j.issn.1671-8348.2014.09.023
辛伐他汀剂量对老年高脂血症患者疗效与安全性的影响
The efficacy and safety of different simvastatin doses on hyperlipidemia in the elderly
刘富春 1王国威 1宋航 1张浩 1高军1
作者信息
- 1. 解放军第324医院药剂科，重庆400020
- 折叠
摘要
Abstract
Objective To study the efficacy and safety of different simvastatin doses on hyperlipidemia in the elderly .Methods 120 patients with hyperlipidemia were randomly divided into two groups ,60 cases in each group ,patients were given simvastatin 10 mg/d(10 mg/d group) or 20 mg/d(20 mg/d group) .Data were collected before and after treatment ,including total cholesterol (TC) ,three acyl glycerin (TG) ,low density lipoprotein cholesterol (LDL-C) ,high density lipoprotein cholesterol (HDL-C) ,treat-ment efficacy and adverse reactions events .Results 3 month after treatment ,TC ,TG ,LDL-C and HDL-C were better than before treatment in both groups(P<0 .05);and the curative effect in 20 mg/d group was better than 10 mg/d group(P<0 .05) .There was no significant difference in incidence of adverse reactions events between the two groups (P>0 .05) .Conclusion 20 mg/d simvasta-tin is better than 10 mg/d simvastatin in efficacy of elderly patients with hyperlipidemia ,and offers a safe and reliable treatment .关键词
高脂血症/老年人/辛伐他汀/治疗效果Key words
hyperlipidemia/elderly/simvastatin/treatment outcome引用本文复制引用
刘富春,王国威,宋航,张浩,高军..辛伐他汀剂量对老年高脂血症患者疗效与安全性的影响[J].重庆医学,2014,(9):1088-1089,1092,3.
