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鸡传染性支气管炎病毒诱导的天然免疫应答研究进展

郑衍生 何怡宁 谢智文 韦平 韦天超 磨美兰

动物医学进展Issue(12):152-155,4.
动物医学进展Issue(12):152-155,4.

鸡传染性支气管炎病毒诱导的天然免疫应答研究进展

Progress on Innate Immune Responses Induced by Avian Infectious Bronchitis Virus

郑衍生 1何怡宁 1谢智文 1韦平 1韦天超 1磨美兰1

作者信息

  • 1. 广西大学动物科学技术学院,广西南宁 530005
  • 折叠

摘要

Abstract

Avian infectious bronchitis (IB)is a highly contagious respiratory disease.The genome of avian infectious bronchitis virus (IBV)is highly variable and its serotypes are multiple and cross protection between different sero-types is poor,which lead to immune failure frequently.Hence,it is very important to disclose the pathogenic mechanisms of IBV.Interaction between virus and the host immune system is a new focus in studying the patho-genesis of IBV,especially the first line of host defense against pathogens,the innate immune system,which play a central role in determining the outcome of infection.The research progress in host innate immune response to IBV infection was focused on pattern recognition receptors,I-interferon,cytokine and chemokine,innate immune cells and complement system in the present review in order to provide information for the study of IBV pathogenesis and prevention and control of IB.

关键词

鸡传染性支气管炎病毒/致病机制/天然免疫

Key words

Avian infectious bronchitis virus/pathogenesis/innate immune

分类

农业科技

引用本文复制引用

郑衍生,何怡宁,谢智文,韦平,韦天超,磨美兰..鸡传染性支气管炎病毒诱导的天然免疫应答研究进展[J].动物医学进展,2013,(12):152-155,4.

基金项目

国家自然科学基金项目(31360611);人力资源和社会保障部留学人员科技活动项目择优资助经费(人社厅函[2012]258号);广西自然科学基金项目 ()

动物医学进展

OA北大核心CSCD

1007-5038

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