动物医学进展Issue(12):152-155,4.
鸡传染性支气管炎病毒诱导的天然免疫应答研究进展
Progress on Innate Immune Responses Induced by Avian Infectious Bronchitis Virus
摘要
Abstract
Avian infectious bronchitis (IB)is a highly contagious respiratory disease.The genome of avian infectious bronchitis virus (IBV)is highly variable and its serotypes are multiple and cross protection between different sero-types is poor,which lead to immune failure frequently.Hence,it is very important to disclose the pathogenic mechanisms of IBV.Interaction between virus and the host immune system is a new focus in studying the patho-genesis of IBV,especially the first line of host defense against pathogens,the innate immune system,which play a central role in determining the outcome of infection.The research progress in host innate immune response to IBV infection was focused on pattern recognition receptors,I-interferon,cytokine and chemokine,innate immune cells and complement system in the present review in order to provide information for the study of IBV pathogenesis and prevention and control of IB.关键词
鸡传染性支气管炎病毒/致病机制/天然免疫Key words
Avian infectious bronchitis virus/pathogenesis/innate immune分类
农业科技引用本文复制引用
郑衍生,何怡宁,谢智文,韦平,韦天超,磨美兰..鸡传染性支气管炎病毒诱导的天然免疫应答研究进展[J].动物医学进展,2013,(12):152-155,4.基金项目
国家自然科学基金项目(31360611);人力资源和社会保障部留学人员科技活动项目择优资助经费(人社厅函[2012]258号);广西自然科学基金项目 ()