动物医学进展Issue(12)：241-243,3.
豚鼠和大鼠被动皮肤过敏试验
Passive Cutaneous Anaphylaxis Test in guinea pigs and Rats
张冬梅 1刘延珍 2单淑香 3朱春花 1闫俊 1谢淑娟4
作者信息
- 1. 山东省医药工业研究所山东省化学药物重点实验室，山东济南 250033
- 2. 山东罗欣药业股份有限公司，山东临沂 276017
- 3. 山东省胸科医院，山东济南 250013
- 4. 山东省标准化研究院，山东济南 250033
- 折叠
摘要
Abstract
Comparison of the different sensitivity of passive cutaneous anaphylaxis(PCA)on guinea pigs, Sprague Dawley(SD)rats and Wistar rats caused by BSA was conducted in order to find more sensitive an-imal model in PCA test.PCA was performed by using guinea pigs,SD rats and Wistar rats,and BSA was taken as allergen.The diameter of dermal Evan′s blue spot and the positive reaction rate were measured to discriminate severity of PCA on three animals.Guinea pigs and rats to BSA have large differences The guinea pigs were the most sensitive animals to BSA.The guinea pig is the best animal model which can be used in PCA test.关键词
被动皮肤过敏试验/豚鼠/SD 大鼠/Wistar 大鼠/牛血清白蛋白Key words
passive cutaneous anaphylaxis test/guinea pig/SD rat/Wistar rat/BSA分类
农业科技引用本文复制引用
张冬梅,刘延珍,单淑香,朱春花,闫俊,谢淑娟..豚鼠和大鼠被动皮肤过敏试验[J].动物医学进展,2013,(12):241-243,3.
