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人参超微粉与细粉的体外溶出度比较

蔡璐 梁少瑜 戴开金 向飞军 罗奇志

南方医科大学学报Issue(10):1547-1550,4.
南方医科大学学报Issue(10):1547-1550,4.

人参超微粉与细粉的体外溶出度比较

Comparison of dissolution properties between Ginseng micropowder and common powder

蔡璐 1梁少瑜 2戴开金 3向飞军 2罗奇志1

作者信息

  • 1. 南方医科大学 肿瘤研究所,广东 广州 510515
  • 2. 康美药业股份有限公司,广东 普宁 515300
  • 3. 南方医科大学 产业管理处,广东 广州 510515
  • 折叠

摘要

Abstract

Objective To compare the dissolution properties of Ginseng micropowder and common powder in vitro and investigate the effect of micronization on dissolution of Ginseng. Methods Five ginsenosides including Rg1, Re, Rf, Rb1, and Rb2 were determined by high performance liquid chromatography, and the dissolution curves of Ginseng micropowder and common powder were drawn. Results The dissolution rates of ginsenosides from micropowder exceeded 90%within 5 min, significantly greater than that from common powder. But when the powders were packed in tea bags, the dissolution rates of ginsenosides were higher from common powder than from micropowder. Conclusion Micronization treatments can promote dissolution of ginsenosides from Ginseng.

关键词

人参皂苷/溶出度/人参超微粉/人参细粉

Key words

ginsenosides/dissolution rate/ginseng micropowder/ginseng common powder

引用本文复制引用

蔡璐,梁少瑜,戴开金,向飞军,罗奇志..人参超微粉与细粉的体外溶出度比较[J].南方医科大学学报,2013,(10):1547-1550,4.

基金项目

广东省自然科学基金博士启动项目(10451051501005775);省部产学研结合项目(2012B091100371);玉屏风及生脉组方微粉化研究 ()

南方医科大学学报

OA北大核心CSCDCSTPCDMEDLINE

1673-4254

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