摘要
Abstract
Objective To evaluate the diagnostic value of ultrasonography in combination with mammography for breast cancer within 2 cm. Methods The PubMed, the Cochrane Library, CNKI, CBM and Wanfang databases (2003/01/01-2013/04/30) were searched for studies of the diagnostic value of ultrasonography in combination with mammography for breast cancer within 2 cm. The quality of the included studies was evaluated according to QUADAS items. The pooled sensitivity (SEN), pooled specificity (SPE), pooled diagnostic odds ratio (DOR), and area under summary receiver operating characteristic curve (AUC) were calculated using Review Manager 5.2 and Meta-DiSc 1.4 software. Results Nine articles were included in the final analysis. The pooled SEN of ultrasonography, mammography and their combination were 0.75, 0.66, and 0.92, the pooled SPE 0.75, 0.83, and 0.82, the pooled DOR 7.11, 8.67, and 60.82, and the AUC 0.7902, 0.8120, and 0.9469, respectively. Conclusion The combination of ultrasonography and mammography can increase the diagnostic accuracy for breast cancer within 2 cm.关键词
乳腺癌/超声/钼靶X线/早期诊断/系统评价/meta分析Key words
breast cancer/ultrasonography/mammography/early diagnosis/systematic review/meta-analysis
