南方医科大学学报Issue(12)：1738-1743,6.DOI:10.3969/j.issn.1673-4254.2013.12.06
中国大陆地区成年人高血压前期发生率及危险因素的meta分析
Incidence and risk factors of prehypertension among adults in mainland China：a meta-analysis
摘要
Abstract
Objective To investigate the incidence and risk factors of prehypertension among adults in mainland China and identify the high-risk population. Methods Six databases including Chinese Biological Medical Literature Database (CBM), Chinese Science and Technology Periodical Database (VIP), China National Knowledge Infrastructure (CNKI), Wanfang Database (WF), PubMed and Web of Knowledge were searched for publications documenting the incidence and risk factors of prehypertension among general population in Chinese adults. Eligible studies were selected according to the inclusion and exclusion criteria for meta-analysis using Stata software and RevMan software. Results Twenty-one published studies were finally included. The results showed that the incidence of prehypertension was 37%in Chinese adults. The pooled SMD (95%confidence interval [CI]) was 0.37 (0.29-0.46) for body mass index, 0.20 (0.12-0.27) for fasting blood glucose (FPG), 0.17 (0.15-0.19) for total cholesterol (TC), 0.22 (0.17-0.27) for triglyceride (TG), 0.13 (0.10-0.15) for low-density lipoprotein cholesterol (LDL-C), and-0.07 (-0.16-0.02) for high-density lipoprotein cholesterol (HDL-C). For smoking, drinking and family history of hypertension, the pooled OR (95%CI) were 1.44 (1.40-1.47), 1.60 (1.44-1.79), and 1.19 (1.04-1.35), respectively. Conclusion The incidence of prehypertension among adults in mainland China is relatively high, especially in males. BMI, FBG, TC, TG, LDL-C, smoking, drinking and family history of hypertension are positively related to prehypertension, and early intervention is recommended to reverse these modifiable risk factors.关键词
高血压前期/发生率/危险因素/meta分析Key words
prehypertension/incidence/risk factors/meta-analysis引用本文复制引用
金楠,李革,李会,陈玲,冷冰..中国大陆地区成年人高血压前期发生率及危险因素的meta分析[J].南方医科大学学报,2013,(12):1738-1743,6.基金项目
“十二五”国家科技支撑计划项目（2011BAI11B01）The National Twelfth Five- year Science and Technology Support Program(2011BAI11B01) （2011BAI11B01）
