摘要
Abstract
Objective To evaluate the application value of high-risk HPV-DNA and thinprep cytology test ( TCT ) in cervical cancer screening among postmenopausal women .Methods Total 346 postmenopausal women receiving common cervical screening in Nantong Maternity and Child Health Hospital were randomly selected to perform high-risk HPV-DNA and TCT check .The cases with positive results received pathological biopsy .Results The difference in sensitivity of HPV-DNA and TCT was not statistically significant (P>0.05).The positive prediction values of TCT and HPV-DNA were 19.05%and 44.64%, respectively, and the difference was statistically significant (χ2 value was 12.91AB and 12.17AC, respectively, both P<0.05).There was no significant difference between the double positive value of TCT combined with HPV and the positive predictive value of single HPV (P>0.05).Taking pathological diagnosis as gold standard , the positive coincidence rate of ASCUS , LSIL, HSIL and SCC was 5.56%, 27.03%, 40.00%and 85.71%, respectively.Conclusion The single high-risk HPV-DNA test can be used as the preferred method of cervical cancer screening among postmenopausal women .关键词
薄层液基细胞学检查/绝经后妇女/宫颈癌/筛查Key words
thinprep cytology test (TCT)/postmenopausal women/cervical cancer/screening分类
医药卫生
