国际生殖健康计划生育杂志Issue(5)：384-386,3.
紧密连接的结构与功能
Tight Junction:Structure and Function
摘要
Abstract
Tight junction is a fundamental junctional complex of the adjacent epithelial cells,with multiple functions including the barrier effect regulating intercellular permeability and maintaining cellular polarity, which was consisted of several protein families including transmembrane proteins (such as occluding, claudin) and peripheral proteins (such as ZO protein). The structure and function of tight junction can be changed by many physio-/pathological factors such as anoxia, hormonal, inflammatory factors and estrogen. Tight junction has already been detected in human uterine endometrium and placenta. Factors of tight junction expressed in those tissues and organs. Abnormality of tight junction may be involved in the pregnancy complications.关键词
紧密连接部/通透性/细胞极性/缺氧Key words
Tight junctions/Permeability/Cell polarity/Anoxia引用本文复制引用
赵海君,钱易(综述),崔毓桂,刘嘉茵(审校)..紧密连接的结构与功能[J].国际生殖健康计划生育杂志,2013,(5):384-386,3.基金项目
国家重点基础研究发展计划（973计划） （）
