国际生殖健康计划生育杂志201306Issue(6)：442-445,4.
辅助生殖技术与出生缺陷
Assisted Reproductive Technology and Birth Defects
摘要
Abstract
Whether assisted reproductive technology (ART) increase or cause birth defects has not been determined. However,the causality of the association of ART and birth defects is probably multifactorial,which may be different with natural conception. The major concern is still whether the ART procedures such as ovarian stimulation,embryo culture media and culture time have a possible negative impact on the ART offspring. Concerns of imprinting disorders related to the ART procedures have also been raised. Moreover,diseases which cause infertility have been shown to affect the risk of birth defects. It is important to emphasize that the vast majority of ART infants are healthy. Future research should be devoted to finding the mechanisms of the association between ART and birth defects. ART treatments could be improved in ways that may lead to decreased birth risks and improved population quality.关键词
不育,女(雌)性/生殖技术,辅助/先天畸形/染色体畸变/基因组印迹Key words
Infertility,female/Reproductive techniques,assisted/Congenital abnormalities/Chromosome aberrations/Genomic imprinting引用本文复制引用
丁婷(综述),乔杰(审校)..辅助生殖技术与出生缺陷[J].国际生殖健康计划生育杂志201306,2013,(6):442-445,4.基金项目
卫生行业科研专项项目 （）
