国际口腔医学杂志Issue(6)：782-785,4.DOI:10.7518/gjkq.2013.06.022
微小核糖核酸在骨重建中的作用
Role of micro ribonucleicacid in bone remodeling
摘要
Abstract
Micro ribonucleicacid(miRNA) is key post-transcriptional regulator of gene expression, which widely exists in all kinds of plants and animals and microorganisms and participates in the biology growth, cell differentiation, apoptosis and so many kinds of life processes. Hence, the formation, differentiation, proliferation and remodeling of bone are closely associated with miRNA. This review will highlight our current understanding of miRNA and mechanisms of action in bone remodeling. An in-depth understanding of the roles of the regulatory miRNA in bone remodeling will be crucial for the development of new therapeutics, which aim at treating bone loss and facilitating fracture repair. Meanwhile, this will raise a new sight of facilitating osseointegration and the success of implants.关键词
微小核糖核酸/骨/骨重建Key words
micro ribonucleicacid/bone/bone remodeling分类
生物科学引用本文复制引用
汪艳(综述),黄慧(审校)..微小核糖核酸在骨重建中的作用[J].国际口腔医学杂志,2013,(6):782-785,4.基金项目
国家自然科学基金资助项目（81170988）；上海市科学技术委员会基金资助项目 （）
