摘要
Abstract
Objective:To investigate the clinal characteristics of acute infectious portal vein thrombosis (PVT) and to explore effective methods to diagnose and treat the disease at the early stage. Methods:The clinical data of 5 patients with acute infectious PVT from 2003 to 2013 were analyzed retrospectively. Results:All patients suffered from abdominal infectious diseases before PVT were diagnosed. One patient was diagnosed by ultrasonography, and all 5 patients were conifrmed by contrast-enhanced CT scan. All patients received the treatment of antibiotics, and 3 combined with anticoagulant therapy. In a result, 4 patiens improved gradually, among whom 2 obtained partial or complete revascularization. One patient gave up therapy because of multiple organ dysfuction. Conclusion:Acute PVT is a rare but severe complication of abdominal infectious diseases, which may start with fever, distention, vomiting, or diarrhea, finally progress to septic shock, hemorrhagic ascites, peritonitis, intestinal obstruction, bowel necrosis, or multiple organ dysfuction. Ultrasonography, particularly contrast-enhanced CT scan is crutial for early diagnosis. Early application of antibiotics plus anticoagulant therapy and resecting necrotic intestine can make patients revascularized and reduce mortality.关键词
感染/门静脉血栓/肠系膜上静脉血栓/肠坏死/抗感染/抗凝Key words
infection/portal vein thrombosis/mesenteric venous thrombosis/intestine necrosis/anti-infection/anti-coagulation