摘要
Abstract
ObjectiveTo investigate the relationship of fibrinogen (FIB), mean platelet volume (MPV) and acute cerebral infarction (ACI). Methods:The level of platelets system platelets (PLT), MPV, plateletcrit, platelet distri-bution width (PDW) and the coagulation system (prothrombin time, international normalized ratio, FIB, activated partial thromboplastin time) of 429 ACI cases (ACI group) and 429 cases of Non-cerebral infarction group (con-trol group) were analyzed. According to the National Institutes of Health stroke Scale (NIHSS) in ACI pa-tients, the ACI group was divided into mild, moderate and severe subgroups. Results:Compared with the con-trol group, the PLT levels were significantly lower ( <0.01) whereas the MPV, PDW and FIB levels were signif-icantly higher ( <0.01) in ACI group. Logistic regression analysis showed that MPV and FIB were independently associated with ACI ( =1.628, 95% :1.427~1 .857;=7.115,95% :4.981~10.164). The FIB level showed no significant correlation with MPV level. The FIB levels between the subgroups of ACI group were sig-nificantly different ( <0.01). In ACI patients, the FIB levels and NIHSS score were positively correlated (=0.451, <0.01). Conclusion:FIB and MPV levels may be the important risk factors for ACI.关键词
急性脑梗死/血小板平均体积/纤维蛋白原/神经功能缺损Key words
acute cerebral infarction/mean platelet volume/fibrinogen/neurological deficit分类
医药卫生
