神经损伤与功能重建Issue(1)：44-46,3.DOI:10.3870/sjsscj.2014.01.011
神经梅毒的临床特征分析
Clinical Characteristics of Neurosyphilis
徐志鹏 1黎红华 1陈文军 1武强 1林琅1
作者信息
- 1. 广州军区武汉总医院神经内科武汉430070
- 折叠
摘要
Abstract
ObjectiveTo investigate the clinical characteristics and early diagnostic evidence of neurosyphilis. Methods: Clinical data of 10 cases with neurosyphilis who were hospitalized from May 2010 to January 2013 were retrospectively analyzed. Results: The initial symptoms of 10 neurosyphilis patients included dementia (3 cases), tabes dosalis (3 cases), cerebral infarction (1 case), meningitis (1 case), Parkinson syndrome (1 case) and epilepsia (1 case). The treponema pallidum particle assay (TPPA) and rapid plasma regain test (RPR) of 10 serum samples were positive. Cerebrospinal fluid (CSF) examination revealed a normal pressure in all the cases.. CSF protein was increased in 9 cases and leukocyte counts (predominantly lymphocytes) were increased in 4 cases. TPPA was positive in 8 CSF samples and RPR in 5. MRI revealed brain atrophy and multiple lesions manifesting T2 high signal intensity and T1 low signal intensity in the brain or spine cord. Most of the patients' symptoms were improved significantly after treatment of syphilis. Conclusion: The diagnosis of neurosyphilis depends on clinical presentation, laboratory and imaging examinations. Early treatment of neurosyphilis can improve the prognosis.关键词
神经梅毒/临床特点/影像学Key words
neurosyphilis/clinical characteristics/imaging分类
医药卫生引用本文复制引用
徐志鹏,黎红华,陈文军,武强,林琅..神经梅毒的临床特征分析[J].神经损伤与功能重建,2014,(1):44-46,3.
