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急性脑出血患者外周血单核细胞 CD36、CD54表达的临床意义

周礼圆 蓝娇 李吕力 庞刚 李燕华 林慧琼

广西医学Issue(12):1595-1597,3.
广西医学Issue(12):1595-1597,3.DOI:10.11675/j.issn.0253-4304.2013.12.06

急性脑出血患者外周血单核细胞 CD36、CD54表达的临床意义

Clinical Significance of Expressions of CD36,CD54 in Peripheral Blood of Patients with Intracerebral Hemorrhage

周礼圆 1蓝娇 2李吕力 1庞刚 3李燕华 1林慧琼1

作者信息

  • 1. 广西壮族自治区人民医院神经内科,南宁市 530021
  • 2. 广西壮族自治区人民医院科研实验中心,南宁市 530021
  • 3. 广西壮族自治区人民医院神经外科,南宁市 530021
  • 折叠

摘要

Abstract

Objective To investigate the changes of CD 36 ,CD54 expressions in monocytes of peripheral blood as well as the characteristics of peripheral blood routine examination among patients with intracerebral hemorrhage (ICH).Methods The blood routine was performed in 31 patients with ICH ( ICH group) and 27 healthy subjects (control group),the CD36,CD54 expressions in monocytes were measured by using flow cytometry .Results Compared to control group,the CD54 expression level,the counting of white blood cell (WBC) and neutrophil ratio increased in ICH group ( P<0 .01 ) .The CD36 expression level of 72-hour ICH-onset group was significantly higher than that of control group(P<0.01).After one-week treatment,the CD54 expression level of ICH group was significantly higher than that of control group (P<0.01).Conclusion The CD36,CD54 expressions of monocytes of peripheral blood among ICH patients up-regulate,which might be involved in the development and progression of ICH with elevated WBC counting .It can be used as an observation index of ICH prognosis .

关键词

脑出血/单核细胞/CD36/CD54

Key words

Intracerebral hemorrhage/Monocyte/CD36/CD54

分类

医药卫生

引用本文复制引用

周礼圆,蓝娇,李吕力,庞刚,李燕华,林慧琼..急性脑出血患者外周血单核细胞 CD36、CD54表达的临床意义[J].广西医学,2013,(12):1595-1597,3.

基金项目

广西卫生厅科研立项课题 ()

广西医学

OACSTPCD

0253-4304

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