河北医学Issue(1)：3-6,4.DOI:10.3969/j.issn.1006-6233.2014.01.002
结核感染对小儿支气管哮喘吸入糖皮质激素治疗长期效果的影响及其机制探讨
The Effect and Mechanism Analsy is of Tuberculosis Infection in the Treatment of Bronchial Asthma with Inhaled Corticosteroids in Children
摘要
Abstract
Objective:To investigate the effect and mechanism of tuberculosis ( TB ) infection in the treatment of bronchial asthma with inhaled corticosteroids ( ICS ) in children .Method: 70 children with bronchial asthma were divided into observing group (35cases with TB) and control group (35 cases without TB) .ICS treatments were put in all the patients and the anti-tuberculosis treatment was used in observing group patients only.The results of lung function and the related indices of immunology were compared be-tween two groups.Result:There was significant difference in the comparison of lung function.The related lung function indexes of observing group were higher than the control group.The Th1/Th2 and interleukin 27 rising as ICS increased with the extension of treatment time.Conclusion:The TB infection can play a posi-tive role in the ICS treatment for children with bronchial asthma , as it maybe have a positive influence to the distribution of T cell subgroup through the impact of IL -27 which would rise in the TB infection .关键词
结/核/支气管哮喘/糖皮质激素Key words
Tuberculosis/Bronchial asthma/Inhaled corticosteroids引用本文复制引用
何邈,段钧,赵瑞秋..结核感染对小儿支气管哮喘吸入糖皮质激素治疗长期效果的影响及其机制探讨[J].河北医学,2014,(1):3-6,4.基金项目
重庆市科委自然科学基金 （）
