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血清β-HCG 孕酮检测在异位妊娠诊断中的临床意义

陈小玲 韦妙成

河北医学Issue(1):34-37,4.
河北医学Issue(1):34-37,4.DOI:10.3969/j.issn.1006-6233.2014.01.013

血清β-HCG 孕酮检测在异位妊娠诊断中的临床意义

The Detection of β-HCG and Progesterone in Pregnancy Women of Ectopic Pregnancy and its Clinical Significance

陈小玲 1韦妙成2

作者信息

  • 1. 广西壮族自治区玉林市第一人民医院妇科,广西 玉林 537000
  • 2. 广西壮族自治区妇幼保健院妇科,广西 南宁 530023
  • 折叠

摘要

Abstract

Objective:To investigate the changes of human chorionic gonadotrophin-β(β-HCG) and progesterone in pregnancy women of ectopic pregnancy ( EP) and explore its clinical significance .Method:A total of 56 pregnancy women of EP were enrolled in the study .Another 40 normal pregnancy women were used as a control.RIA analysis was used to determine the serum level ofβ-HCG and progesterone.Results:Interval increasing rate of β-HCG and serum level of progesterone with 48 hours was ( 28 .5 ±2 .4 )% and (22.6±1.8)nmol/L in EP group, which was lower than that in control group(124.6±7.5)%and (115.7± 6.9)nmol/L, P<0.01.The sensitivity, specificity and accuracy of progesterone detection was 69.6%, 70. 0%, and 69 .8%.The sensitivity , specificity and accuracy of β-HCG detection was 71 .4%, 72 .5% and 71 .9%.The sensitivity , specificity and accuracy of β-HCG combined with progesterone detection was 92 . 9%, 92 .5%and 92 .7%, which was better than that of β-HCG or progesterone detection .Conclusion:The β-HCG combined with progesterone detection can be used to early diagnosis of EP, and which was wor-thy to promote the clinical application .

关键词

异位妊娠/人绒毛膜促性腺激素β亚体//

Key words

Ectopic pregnancy(EP)/Human chorionic gonadotrophin-β(β-HCG)/Progester-one

引用本文复制引用

陈小玲,韦妙成..血清β-HCG 孕酮检测在异位妊娠诊断中的临床意义[J].河北医学,2014,(1):34-37,4.

河北医学

OACSTPCD

1006-6233

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