郑州大学学报（医学版）Issue(4)：466-469,4.DOI:10.3969/j.issn.1671-6825.2013.04.009
大鼠丘脑中央下核 GABA 纤维终末与腹外侧眶皮质投射神经元的突触联系
Synaptic connections between GABA terminals and neurons projecting to ventrolateral orbital cortex in rat thalamic nucleus submedius
摘要
Abstract
Aim:To study the synaptic connections between GABA ergic terminals and the neurons which project to the ventrolateral orbital cortex(VLO) in the rat thalamic nucleus submedius (Sm).Methods:Eighteen rats were fixed in the stereotaxic apparatus after anesthesia .The Horse radish peroxidase-retrograde tracing method was used in VLO .After 48 h, the double-labeling immunohistochemical electron microscopic technique ( pre-embedding histochemical detection of HRP combined with pre-embedding GABA-immunohistochemical technique ) was used to observe the synaptic connections between GABA ergic terminals and the neurons which project to the VLO in Sm .Results: Under optical microscope , in Sm, there were large number of GABA positive terminals and few positive neurons .Under electron microscope , the sym-metrical and(or) asymmetrical synaptic connections between GABA positive terminals and HRP-retrograde tracing labeled cell bodies and dendrites were observed .Conclusion:GABA positive terminals make synaptic connections with the projec-tion neuron bodies and dendrites from Sm to VLO .关键词
丘脑中央下核/突触/GABA/大鼠Key words
thalamic nucleus submedius/synapse/GABA/rat分类
医药卫生引用本文复制引用
罗阿丽,王唯析,强辉,靳辉,陈国敏..大鼠丘脑中央下核 GABA 纤维终末与腹外侧眶皮质投射神经元的突触联系[J].郑州大学学报（医学版）,2013,(4):466-469,4.基金项目
陕西省自然科学基金资助项目2006 C205 （）
