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特发性弱精子症患者精子中 TCTE3的表达

李玉山 吉晓菲 王全先 杨险峰 潘周辉 胡耀龙

郑州大学学报(医学版)Issue(1):83-85,3.
郑州大学学报(医学版)Issue(1):83-85,3.DOI:10.3969/j.issn.1671-6825.2014.01.023

特发性弱精子症患者精子中 TCTE3的表达

Expression of TCTE3 in spermatozoa of idiopathic asthenozoospermic pa-tients

李玉山 1吉晓菲 1王全先 1杨险峰 1潘周辉 1胡耀龙1

作者信息

  • 1. 郑州大学第三附属医院人类精子库郑州450052
  • 折叠

摘要

Abstract

Aim:To explore the relationship of T-complex associated testis expressed 3(TCTE3) with idiopathic asthe-nozoospermia .Methods:The mRNA and protein expressions of TCTE 3 in 30 cases of normal adult male and 30 cases of idi-opathic asthenozoospermia semen samples were detected by using RT-PCR and Western blot .Results:The relative expres-sion levels of TCTE3 mRNA and protein in the idiopathic asthenozoospermia group were significantly lower than those in the normal control group(t=3.038 and 2.460,P=0.005 and 0.017).Conclusion: The reduced expression of TCTE3 may play an important role in the incidence of idiopathic asthenozoospermia .

关键词

T复合体相关睾丸表达3/特发性弱精子症/轴丝动力蛋白

Key words

T-complex associated testis expressed 3/idiopathic asthenozoospermia/axonemal dynein

分类

医药卫生

引用本文复制引用

李玉山,吉晓菲,王全先,杨险峰,潘周辉,胡耀龙..特发性弱精子症患者精子中 TCTE3的表达[J].郑州大学学报(医学版),2014,(1):83-85,3.

基金项目

郑州市科技攻关计划项目2010S0828 ()

郑州大学学报(医学版)

OA北大核心CSTPCD

1671-6825

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