郑州大学学报（医学版）Issue(2)：227-229,3.DOI:10.13705/j.issn.1671-6825.2014.02.023
侵袭性牙周炎患者牙龈组织中 MMP-1、MMP-8和 MMP-13蛋白的表达
Expressions of MMP-1,MMP-8 and MMP-13 in gingival tissue of patients with aggressive periodontitis
摘要
Abstract
Aim:To analyze the roles of three collagenases (MMP-1,MMP-8 and MMP-13) in the pathogenesis of ag-gressive periodontitis(AgP).Methods:The expressions of MMP-1, MMP-8 and MMP-13 in gingival tissue of 30 patients with AgP and 35 healthy controls were detected by immunohistochemistry method .Results: Low expressions of MMP-1, MMP-8 and MMP-13 were shown in healthy control group .Higher expressions of MMP-1 and MMP-8 were found in the AgP group compared with those of healthy control group (Z=3.980 and 2.990, P<0.05).Conclusion: MMP-1 and MMP-8 may play an important role in the development of AgP .关键词
侵袭性牙周炎/MMP-1/MMP-8/MMP-13/胶原酶Key words
aggressive periodontitis/MMP-1/MMP-8/MMP-13/collagenase分类
医药卫生引用本文复制引用
赵红宇,张淼,岳新新,轩东英,刘林嶓,周磊..侵袭性牙周炎患者牙龈组织中 MMP-1、MMP-8和 MMP-13蛋白的表达[J].郑州大学学报（医学版）,2014,(2):227-229,3.基金项目
广东省科技计划项目00204390134483040 （）
