化工进展Issue(1)：174-177,186,5.DOI:10.3969/j.issn.1000-6613.2014.01.030
壳聚糖修饰磁性纳米粒子对BSA的吸附性能
Adsorption of bovine serum albumin on chitosan modified magnetic nanoparticles
摘要
Abstract
Chitosan was grafted onto the surface of Fe3O4 magnetic nanoparticles fabricated by a chemical coprecipitation method by using (3-chloropropyl) trimethoxysilane as a coupling agent. The modified magnetic nanoparticles were characterized by infrared spectroscopy (FTIR),X-ray diffraction (XRD),scanning electron microscopy (SEM) and thermal gravimetric analysis (TGA). The adsorption properties of the magnetic nano-adsorbent for BSA were investigated under different conditions, including adsorption time,pH and concentration of bovine serum albumin. The size of nanoparticles was about 20 nm,and chitosan made up 15.40% of the weight of the modified Fe3O4 magnetic nanoparticles. Compared with Fe3O4 nanoparticles,chitosan modified nanoparticles showed higher BSA adsorption capacity.关键词
纳米粒子/表面/牛血清白蛋白/壳聚糖/蛋白质Key words
nanoparticles/surface/bovine serum albumin/chitosan/protein分类
通用工业技术引用本文复制引用
郑红,韩景田,丁媛媛,杨帆..壳聚糖修饰磁性纳米粒子对BSA的吸附性能[J].化工进展,2014,(1):174-177,186,5.基金项目
山东科技发展计划（2011YD21006）及滨州医学院博士启动基金（511094）项目。 （）
