化工进展Issue(1)：247-252,6.DOI:10.3969/j.issn.1000-6613.2014.01.045
复合萃取剂提取林可霉素机理及填料萃取塔中试研究
Study of extracting Lincomycin with composite extractant and the pilot test on packed extraction column
高灿 1常宏委 1陆莹莹 1申龙 1高瑞昶1
作者信息
摘要
Abstract
The macroscopic property and mass transfer enhancement of extracting Lincomycin with composite extractant (n-octanol and kerosene) in packed extraction column was studied in this paper. The structure of extracted complex and reaction equilibrium constant were determined by the slope method,which could contribute to the improvement of equipment and mass transfer enhancement. In order to improve the extraction efficiency,factors such as pH of the solution,volume ratio of the water phase to the organic phase,packing type,and distribution plates were considered. The results showed that in the extraction process of Lincomycin with n-octanol,the reaction equilibrium constant was 0.072,the optimum content of n-octanol in composite extractant was 0.8 (volume fraction) , the optimum pH of the extraction solution ranged from 10 to 11 , the optimum volume ratio of the water phase to the organic phase was 3. Limited extraction efficiency was found to present in both structured packing and bulk packing extraction column. Distribution plates could significantly enhance the mass transfer in packed extraction column , with a maximum unit volume treatment capacity of 12.8 times compared to the extraction tank,and the circulation volume of extractant could be greatly reduced. The results can be used for guiding practical application of packed extraction column in Lincomycin extraction.关键词
林可霉素/宏观特性/分布盘/填料萃取塔Key words
lincomycin/macroscopic property/distribution plates/packed extraction column分类
化学化工引用本文复制引用
高灿,常宏委,陆莹莹,申龙,高瑞昶..复合萃取剂提取林可霉素机理及填料萃取塔中试研究[J].化工进展,2014,(1):247-252,6.
