化工进展Issue(2)：463-469,7.DOI:10.3969/j.issn.1000-6613.2014.02.034
响应面分析法优化壳聚糖复合海绵的制备工艺
Optimizing the preparation technology of chitosan composite sponge by response surface method
摘要
Abstract
In order to determine the optimal preparation condition of chitosan composite sponge,the factors and their levels were established first by single factor experiment,and then response surface method was used on the basis of single factor experiment via design concept of the Box-Benhnken center combination experiment. The result shows that,the optimal preparation condition of chitosan composite sponge is that the stirring speed is 541 r/min,the mass percent of sodium hyaluronate is 14%, the ratio of chitosan and sodium alginate is 3.71∶1,the theoretical tensile strength is 0.1652 MPa,and the actual tensile strength is 0.1709 MPa. The preparation technology of chitosan composite sponge has been optimized by response surface method. The sponge material has a good performance on water absorption and water retention. The vesicular structure of the sponge is uniform and multi-level.关键词
响应面分析/壳聚糖复合海绵/制备/优化Key words
response surface analysis/chitosan composite sponge/preparation/optimization分类
化学化工引用本文复制引用
刘传荣,陈思浩,郑玉林,陈玉双,杨秋杰,周超,朱同贺,楼建中..响应面分析法优化壳聚糖复合海绵的制备工艺[J].化工进展,2014,(2):463-469,7.基金项目
上海高校学科专业建设项目（11XK18B，XKCZ1205）及上海市科委地方高校能力建设项目（11490501500）。 （）
