化工学报Issue(3)：954-959,6.DOI:10.3969/j.issn.0438-1157.2014.03.027
PAA-g-ZrO2复合膜过滤牛血清蛋白过程的污染阻力分析
Analysis of fouling resistance of PAA-g-ZrO2 composite membrane in filtrating BSA solution
摘要
Abstract
Fouling of PAA-g-ZrO2 composite membrane by BSA solution was investigated in conjunction with analysis of membrane total resistances and resistances distribution. The total resistances of the PAA-g-ZrO2 composite membrane and ZrO2 membrane increased with increasing filtration time, but the growth trend of the PAA-g-ZrO2 composite membrane total resistances was lower than that of the ZrO2 membrane. The fouling resistance of the ZrO2 membrane was Rcp (concentration polarization resistance)-dominant, while Rcp and Rm (membrane resistance) controlled the PAA-g-ZrO2 composite membrane separation process. The internal plugging resistance (Rif) of the PAA-g-ZrO2 composite membrane was just half of that of the ZrO2 membrane. The membrane resistance of PAA-g-ZrO2 composite membrane increased with increasing pH. The densely packed brush-shaped structure of the PAA chains was considered to be responsible for reducing the protein adsorption on the membrane surface. Furthermore, the PAA-g-ZrO2 composite membrane displayed high pH-sensitivity for BSA solutions, and could resist protein fouling in high pH applications.关键词
膜/过滤/膜污染/蛋白质/丙烯酸/pH敏感/膜阻力Key words
membranes/filtration/fouling/protein/acrylic acid/pH-sensitivity/membrane resistance分类
化学化工引用本文复制引用
周守勇,张艳,薛爱莲,王辉,李梅生,赵宜江,邢卫红..PAA-g-ZrO2复合膜过滤牛血清蛋白过程的污染阻力分析[J].化工学报,2014,(3):954-959,6.基金项目
国家自然科学基金项目(20976067)；江苏省高校自然科学研究项目（12KJD530001）；江苏省科技支撑计划(工业)项目(BE2013080)；江苏省低维材料化学重点建设实验室开放课题（JSKC12115)；江苏省高校“青蓝工程”资助项目；江苏省六大人才高峰项目；江苏省政府留学基金项目@@@@supported by the National Natural Science Foundation of China (20976067), the Natural Science Foundation of Jiangsu Education Department (12KJD530001), the Jiangsu Province Science and Technology Support Program (BE2013080), the Open Project Program of Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials (JSKC12115), the Jiangsu Qing Lan Project, the Six Projects Sponsoring Talent Summits of Jiangsu Province and the Jiangsu Government Scholarship for Overseas Studies （20976067）
