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毛脉酸模体外抗菌及抗病毒作用的实验研究

刘奂 马微微 岳赛男 任秀明 郭美 王振月

哈尔滨商业大学学报(自然科学版)Issue(2):154-156,171,4.
哈尔滨商业大学学报(自然科学版)Issue(2):154-156,171,4.

毛脉酸模体外抗菌及抗病毒作用的实验研究

In vitro antibacterial and antiviral activity of Rumex gmelini

刘奂 1马微微 1岳赛男 1任秀明 1郭美 1王振月1

作者信息

  • 1. 黑龙江中医药大学,哈尔滨,150040
  • 折叠

摘要

Abstract

To explore the antibacterial and antiviral actions of Rumex gmelini the antibacterial activity in vitro of Rumex gmelini extracted in different ways against common several kinds of bacteria were tested by double -diluted method , and the minimum inhibition concentration ( MIC) and minimum bactericidal concentration ( MBC) of them was detected .The antiviral activities of extracts on influenza virus was assessed by cytopathic effect ( CPE) method.The 50%toxic concentration ( TC50 ) , 50% inhibitory concentration ( IC50 ) and selective index ( SI) of the different extract and its two fractions were determined by Reed -Muench meth-od.Results indicated that water extract and 70% alcohol quenching liquid both had strong antibacterial and antiviral activities .Water extract and alcohol extract had stronger inhibition of influenza virus.Half inhibition of volume concentration (IC50) were 6.2 mg/mL and <0. 4 mg/mL.The antibacterial and antiviral activity of the alcohol extraction of Rumex gmelini is a high active fraction.It’s worth further development and utilization .

关键词

毛脉酸模/抗菌/抗病毒

Key words

Rumex gmelini/antibacterial/antiviral

分类

医药卫生

引用本文复制引用

刘奂,马微微,岳赛男,任秀明,郭美,王振月..毛脉酸模体外抗菌及抗病毒作用的实验研究[J].哈尔滨商业大学学报(自然科学版),2014,(2):154-156,171,4.

基金项目

国家自然科学基金项目(30970300);哈尔滨市科技创新人才研究专项基金项目(2010rfxxs031). ()

哈尔滨商业大学学报(自然科学版)

1672-0946

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