哈尔滨商业大学学报(自然科学版)Issue(2):157-160,4.
石蒜碱对人白血病细胞K562凋亡作用的研究
Study on apoptosis of human leukemia cell line K562 induced by lycorine
摘要
Abstract
In order to investigate the apoptosis of human leukemia cell line K 562 induced by lycorine , this paper detected the cytotoxicity of lycorine to K 562 by MTT assay , and the re-sult showed that the IC 50 was 16.000μmol/L.Flow cytometry assay showed that the apopto-sis of K562 increased in a dose-dependent manner .The confocal laser scanning microscopy observed that the membrane potential of K 562 also decreased in a dose-dependent manner . All data indicated that lycorine could induce apoptosis of K 562 and decrease its membrane potential .关键词
石蒜碱/人白血病细胞K562/细胞凋亡Key words
lycorine/human leukemia cell line K562/apoptosis分类
医药卫生引用本文复制引用
于淼,于洋,刘林涛..石蒜碱对人白血病细胞K562凋亡作用的研究[J].哈尔滨商业大学学报(自然科学版),2014,(2):157-160,4.基金项目
黑龙江省教育厅科技项目(1211135). ()