河南农业科学Issue(12)：129-132,4.
猪CB1基因的生物信息学分析
Bioinformatics Analysis on Cannabinoid Receptors 1 of Swine
摘要
Abstract
In the study ,the phylogenetic relationship of the coding sequences (CDS) of CB1 gene between swine and other 21 species ,and the physicochemical characters and structural properties of CB1-encoding protein in swine were analyzed with bioinformatics methods .The results showed that the homology of CB1 gene was high as purifying selection could exist in its evolution .The CB1 protein was a hydrophobic transmembrane protein consisting of 472 amino acid residues without signal peptide .The primary structure of the protein CB1 contained 23 phosphorylation sites and 6 glycosylation sites ,the secondary structure was made up of 47 .67% of α-helix , 39 .62% of random coil ,12 .71% of extended strand ,the tertiary structure was composed of 7α-heli-ces and random coil .The results indicate that CB1 maybe is a housekeeping gene of mammals and the 7 connected α-helices are active sites of CB1 in swine .关键词
猪/大麻素1型受体基因/生物信息学Key words
swine/cannabinoid receptor 1 gene/bioinformatics分类
农业科技引用本文复制引用
魏星灿,贾青,陶隽,胡慧艳..猪CB1基因的生物信息学分析[J].河南农业科学,2013,(12):129-132,4.基金项目
河北省现代农业产业技术体系创新团队建设专项资金项目 （）
