中国实用神经疾病杂志Issue(6)：21-23,3.
老年急性缺血性脑卒中患者血浆同型半胱氨酸水平与颈动脉粥样硬化的关系研究
The study on correlation between plasma levels of homocysteine and carotid atherosclerosis in elderly patients with acute ischemic stroke
侯英娟 1李京 1马亚玲 1张羽凡1
作者信息
- 1. 陕西榆林市第一医院神经内科 榆林 718000
- 折叠
摘要
Abstract
Objective To investigate the correlation between plasma levels of homocysteine and carotid artery atheroscle-rotic plaque in elderly patients with acute ischemic stroke (ACI). Methods 85 patients with ACI were chosen for the study from January 2010 to December 2012. All patients were divided into 33case with CAS plaque (observation group) and 52 case without CAS plaque (control group). plasma level of Hcy in two groups were measured and the correlation between CAS grad-ing and Hcy levels were analyzed.Results The Hcy concentration of observation group was (19.56 ± 5.23) umol/L ,signifi-cantly higher than that of the control group (12.45 ± 2.54) umol/L ,and the difference was statistically significant (P<0.05). The incidence of hyperhomocysteinemia in observation group was significantly higher than that of control group (15.15% vs 36.54% ) ,the difference was statistically significant (P<0.05). Single factor analysis showed that Hcy levels had a positive correlation with CAS grading (r=0.542 ,P=0.002). The plasma level of Hcy in CAS grade 4 group was significantly higher than those in other grad group ,the difference was statistically significant (P<0.05). Conclusion CAS plaque formation may be associated with elevated plasma level of Hcy in elderly patients with ACI.关键词
急性缺血性脑卒中/同型半胱氨酸/颈动脉斑块/相关性Key words
Acute ischemic stroke/Homocysteine/Carotid artery plaque/Correlation分类
医药卫生引用本文复制引用
侯英娟,李京,马亚玲,张羽凡..老年急性缺血性脑卒中患者血浆同型半胱氨酸水平与颈动脉粥样硬化的关系研究[J].中国实用神经疾病杂志,2014,(6):21-23,3.
